Breathwork, Cold Exposure, and Mindset Training

3 Free video lessons with Wim Hof.

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THE SCIENCE

Tested. Published. Peer-reviewed.

24 peer-reviewed studies, from Radboud UMC to PNAS and Nature, pushing the boundaries of what we know about the human body.

THE EXPERIENCE

Start with a breathing session with Wim Hof

3 free video lessons. The first starts right away with a breathing exercise. You do it, you feel it, immediately.

3 lessons · ~10 min each · no credit card required

No experience or equipment needed.

PRACTICED WORLDWIDE

A global movement

Thousands of people around the world practice the Wim Hof Method every day.

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Radboud UMC

2011

The experiment that started it all

Radboud University Medical Centre n = 1 (Wim Hof)

WHAT THAT MEANS FOR YOU

For years, no research institution would take Wim Hof seriously. In 2011, Radboud University Medical Centre finally agreed to test him. They injected him with a bacterial toxin that normally triggers a strong immune response. His body barely reacted. His inflammatory response was less than half of what healthy volunteers showed. The researchers didn’t expect the result. The data suggested otherwise.

THE RESEARCH

Radboud UMC injected Wim Hof with a bacterial toxin (E. coli LPS), the same substance used in immunology research to trigger a controlled inflammatory response. Healthy volunteers typically develop flu-like symptoms within hours. Wim’s levels of pro-inflammatory proteins were less than half those of the control group. This unexpected result led the same team to design the 2014 follow-up: could ordinary people learn the same ability?

PNAS 2014

Radboud UMC

Reduced inflammation in trained beginners after 10 days

Radboud University Medical Centre n = 24

WHAT THIS MEANS FOR YOU

Can ordinary people learn what Wim Hof does? Radboud UMC trained 12 volunteers for 10 days, then injected them with the same bacterial endotoxin. The trained group showed 53% less inflammation. Published in PNAS, one of the world’s most cited scientific journals.

THE RESEARCH

24 healthy male volunteers were split into two groups: 12 trained in the Wim Hof Method for 10 days, 12 as a control. All were injected with bacterial endotoxin. The trained group produced 194% more of the anti-inflammatory protein IL-10 and showed 53% less TNF-α, 57% less IL-6, and 51% less IL-8, all markers of inflammation. They also reported fewer flu-like symptoms. This was the first controlled study showing that the autonomic nervous system and immune response can be voluntarily influenced.

Scientific Reports 2025

Nature

404 people, 29 days: the effects kept growing

Nature Portfolio n = 404

WHAT THIS MEANS FOR YOU

The largest Wim Hof Method study to date tracked 404 participants over 29 days. Both groups practicing the method, whether in-person or remotely, reported significantly more energy, sharper thinking, and greater resilience to stress compared to a meditation control group. The effects were not instant. They built up day by day.

THE RESEARCH

404 healthy adults were divided into three groups: Wim Hof Method in-person, Wim Hof Method remote, and meditation. Over 29 days, both Wim Hof Method groups scored significantly higher than the meditation group on self-reported energy, mental clarity, and stress resilience. The effects were cumulative, growing stronger with consistent daily practice. Notably, both in-person and remote training produced comparable results, suggesting the method can be learned effectively from home.

Neurological Sciences 2025

Reduced disease activity and improved quality of life in multiple sclerosis

Multiple Sclerosis Research n = 60

WHAT THIS MEANS FOR YOU

In people with multiple sclerosis, the immune system attacks the protective insulation around nerves. After 12 weeks of practicing the Wim Hof Method, participants showed significantly lower levels of the specific inflammation markers that drive this damage. They also reported improvements in thinking, energy, and anxiety.

THE RESEARCH

60 MS patients were randomized into a Wim Hof Method group and a control group. After 12 weeks, the Wim Hof Method group showed significant reductions in IL-17A and IFN-γ, two inflammatory proteins directly involved in the breakdown of myelin, the protective coating around nerves. The Wim Hof Method group also showed significantly greater improvement in cognitive function, fatigue levels, and anxiety scores compared to the control group.

PLOS ONE 2019

Amsterdam UMC

Reduced pain and improved quality of life in 8 weeks

Amsterdam UMC n = 24

WHAT THIS MEANS FOR YOU

Axial spondyloarthritis causes chronic pain in the joints and spine. After 8 weeks of practicing the Wim Hof Method, participants showed lower disease activity and a significant improvement in both physical and mental quality of life.

THE RESEARCH

24 patients with axial spondyloarthritis were split into a Wim Hof Method group (n=13) and a control group (n=11). The Wim Hof Method group showed reductions across all disease activity markers: ESR, BASDAI, ASDAS-CRP, and serum calprotectin. Quality of life improved significantly on both the physical and mental components of the SF-36 health survey (p=0.004 for both).

Psychosomatic Medicine 2022

Radboud UMC

Scientists discovered why the method works

Radboud University Medical Centre n = 48

WHAT THIS MEANS FOR YOU

What makes the Wim Hof Method work? This Radboud UMC study separated the ingredients. The breathing technique was the active component. Cold exposure alone did not significantly reduce inflammation. It is the way you breathe that makes the difference.

THE RESEARCH

48 healthy young adults were divided into groups to isolate the effects of breathing and cold exposure. The group practicing the Wim Hof breathing technique with breath retention showed significantly lower levels of inflammatory proteins (TNF-α, IL-6, IL-8) and higher levels of the anti-inflammatory protein IL-10. Cold exposure alone showed no significant effect on these markers. Symptoms resolved fastest in the group that combined breathing with cold exposure.

NeuroImage 2018

Wayne State University

Brain activity linked to pain regulation during cold exposure and breathing

Wayne State University n = 1 (Wim Hof)

WHAT THAT MEANS FOR YOU

Brain scans of Wim Hof during his breathing practice revealed something unexpected: he activated a brain region linked to pain regulation that scientists previously believed could not be consciously controlled. This was the first neuroimaging evidence that the autonomic nervous system can be willfully influenced.

THE RESEARCH

Researchers at Wayne State University used fMRI and PET imaging to scan Wim Hof’s brain during controlled cold exposure. They observed significant activation of the periaqueductal gray (PAG), a brainstem region associated with pain regulation. The researchers hypothesized that this activation may trigger the body’s own pain relief system through opioid and cannabinoid pathways. While this was a study of one individual, it provided the first brain imaging evidence of willful autonomic regulation and inspired a new generation of research with larger groups.

breathing with wim hof method

15-MINUTE RESET

Breathing

Calm the nervous system. Drop into deep relaxation.

The technique is simple and can be learned in one session.

Sit or lie down somewhere comfortable. Take 30 deep breaths, in through the nose or mouth, letting the belly rise, then let the breath fall out without forcing it. After the last exhale, hold your breath until your body naturally asks for air again. Then take one deep breath in, hold for about 10 to 15 seconds, and let go. Repeat this cycle 3 to 4 times.

You might feel lightheaded or notice tingling in your hands or face, especially the first time. That’s normal and passes quickly. With each round, the body tends to settle into a calmer state that can stay with you afterwards.

Never practice in water, in the shower, or while driving.

Lesson 1 of the Mini Class is a guided breathing session. Start there.

Want to build a consistent practice?
Download the Wim Hof app

cold therapy wim hof method

BUILD RESILIENCE

Cold Exposure

Start with a 30-second cold shower. Train your body to adapt under stress.

The first cold shower is a small victory. That moment under the tap, where everything in you says no, is part of it. Turn it anyway.

The second one is easier. Within a few days, you start to notice the change. The breath catches less. The cold feels less like a shock and more like a reset.

You don’t need an ice bath to begin. Just finish your regular shower with 30 seconds of cold water, then add a little more each week.

Over time, things shift. You wake up more easily. Sleep feels deeper. Your body responds faster. Energy becomes more stable.

The key is gradual. Not pushing, but building. Cold isn’t about suffering. It’s about training how you respond.

Listen to your body. Start where you are.

Lesson 2 of the Mini Class walks you through your first cold exposure.

Ready for the real thing?
Shop the Wim Hof Ice Plunge

commitment with wim hof method

MENTAL TRAINING

Mindset

The mind under control is your best friend. Stay present under pressure.

Most of life runs on habit. Alarm, commute, meals, screens, sleep. You move through it without thinking.

This is where mindset becomes practical. Not thinking differently, but noticing what’s happening in you without reacting straight away. Thoughts, tension, discomfort. And staying with it anyway.

Breathing and cold are where you see it clearly. You keep going when it gets uncomfortable. You don’t immediately act on the urge to stop.

At first, it takes effort. Then it becomes more natural. Less reaction. More space.

And over time, that changes how you move through everything.

Lesson 3 of the Mini Class is about exactly this.

Ready to go deeper?
Explore the Fundamentals course

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